University of Colorado Post-Doctoral Fellow in Aurora, Colorado
University of Colorado – School of Medicine
The University of Colorado Denver l Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.
This position reports directly to Dr. Hopp in the Division of Renal Diseases and Hypertension and is responsible for understanding the importance of the cystic microenvironment in Polycystic Kidney Disease progression. This position supervises graduate students and PRAs in the Hopp laboratory.
Areas of Responsibility/Scope of Research
Dr. Hopp’s laboratory studies Autosomal Dominant PKD (ADPKD) pathomechanisms. ADPKD is the most common monogenic renal disease worldwide with currently limited therapeutic options to alleviate disease burden characterized by progressive cyst growth and end stage renal disease. ADPKD has many molecular and cellular commonalities with cancer, in which the microenvironment has shown tremendous potential for therapeutic intervention.
We are interested in studying the role of the microenvironment, specifically immune cells, in ADPKD progression and apply the knowledge gained from the cancer field to PKD. The project makes heavily use of PKD mouse models to understand the interplay between immune cells and cystic renal epithelial cells. Hence, a post-doctoral applicant should be familiar with utilizing mouse/rat models for basic/translational research including knowledge about mouse colony maintenance, genotyping, breeding of single, double, and triple transgenic lines, preclinical studies, and histopathological analyses. Additionally, background knowledge in immunology and immunological techniques (flow cytometry) are highly encouraged and experience with basic cellular, molecular techniques (Western blotting, PCR/qPCR, IHC/IF) and statistical analyses (Microsoft Excel/PRISM/JMP) are required.
Graduation from an accredited college or university with a PhD and or MD/PhD.
Minimum of 2-year(s) experience in research
Desired or Preferred:
PhD in the field of PKD research and/or immunology
Proven experience and familiarity with PKD systems and procedures
Proven ability to work independently within a research lab
Experience in mentoring PhD students/laboratory technicians
Excellent communication skills in English
Demonstrated ability/proficiency/excellence computer software, equipment operation, or research technical skills
Salary and Benefits:
Salary is commensurate with skills and experience and based on NIH guidelines. The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located atEmployee Services.
Postdoc-specific benefits are found here: http://www.ucdenver.edu/faculty_staff/research/postdoctoral/Pages/default.aspx
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Diversity and Equity:
Please click here for information on disability accommodations:http://www.ucdenver.edu/about/departments/HR/jobs/Pages/JobsatCUDenver.aspx
The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.
Organization: *H0001 -- Anschutz Medical Campus
Title: Post-Doctoral Fellow
Requisition ID: 14110